Search on: HISTONE DEMETHYLASES 
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Descriptor English:   Histone Demethylases 
Descriptor Spanish:   Histona Demetilasas 
Descriptor Portuguese:   Histona Desmetilases 
Tree Number:   D08.811.682.662.582.475
Definition English:   Enzymes that catalyse the removal of methyl groups from LYSINE or ARGININE residues found on HISTONES. Many histone demethylases generally function through an oxidoreductive mechanism. 
History Note English:   2010 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   53606 
Unique Identifier:   D056466 

Occurrence in VHL: 		 

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